Apoptosis

TNF Ligand Family:

CD40LG (TNFSF5), FASLG (TNFSF6), LTA, TNF, TNFSF10, CD70, TNFSF8.

TNF Receptor Family:

CD40 (TNFRSF5), FAS (TNFRSF6), LTBR, TNFRSF10A, TNFRSF10B, TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFRSF21, TNFRSF25, CD27, TNFRSF9. 山东大学齐鲁医院妇科张师前

Bcl-2 Family:

BAD, BAG1, BAG3, BAG4, BAK1, BAX, BCL2, BCL2A1, BCL2L1, BCL2L10, BCL2L11, BCL2L2, BCLAF1, BID, BIK, BNIP1, BNIP2, BNIP3, BNIP3L, HRK, MCL1.

Caspase Family:

CASP1, CASP10, CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9.

IAP Family:

NAIP, BIRC2, BIRC3, BIRC4, BIRC6, BIRC8.

TRAF Family:

TRAF2, TRAF3, TRAF4.

CARD Family:

APAF1, BCL10, BIRC2, BIRC3, NOD1, CARD6, CARD8, CASP1, CASP2, CASP4, CASP5, CASP9, CRADD, NOL3, PYCARD, RIPK2.

Death Domain Family:

CRADD, DAPK1, FADD, FAS (TNFRSF6), TNFRSF10A, TNFRSF10B, TNFRSF11B, TNFRSF1A, TNFRSF21, TNFRSF25, TRADD.

Death Effector Domain Family:

CASP8, CASP10, CFLAR, FADD.

CIDE Domain Family:

CIDEA, CIDEB, DFFA.

p53 and DNA Damage Response:

ABL1, AKT1, APAF1, BAD, BAX, BCL2, BCL2L1, BID, CASP3, CASP6, CASP7, CASP9, GADD45A, TP53, TP53BP2, TP73.

Anti-Apoptosis:

AKT1, BAG1, BAG3, BCL2, BCL2A1, BCL2L1, BCL2L10, BCL2L2, BFAR, NAIP, BIRC2, BIRC3, BIRC4, BIRC6, BIRC8, BNIP1, BNIP2, BNIP3, BRAF, CASP2, CFLAR, FAS (TNFRSF6), IGF1R, MCL1, TNF, CD27.