p53 Signaling Pathway

Apoptosis Genes:
Induction of Apoptosis: BAX, BID, CDKN1A, CRADD, EI24, FADD, FASLG (TNFSF6), FOXO3, PCBP4, PRKCA, TNFRSF10B, TP53, TP73, TP73L.
Anti-Apoptosis: BCL2, BCL2A1, BIRC5, CASP2, HDAC1, IGF1R, MCL1, NFKB1, RELA, TNF, TNFRSF10D.山东大学齐鲁医院妇科张师前
Other Apoptosis Genes: APAF1, BRCA1, CASP9, E2F1, GADD45A, GML, LRDD, P53AIP1, SIAH1, SIRT1, TP53BP2, TRAF2.

Cell Cycle Genes:
Cell Cycle Arrest: CDKN1A, CDKN2A, CHEK1, CHEK2, GADD45A, GML, MYC, PCAF, PCBP4, RPRM, SESN1, SESN2.
Cell Cycle Checkpoint: ATR, BRCA1, CCNE2, CCNG2, CDKN2A, RB1, TP53.
Negative Regulation of the Cell Cycle: ATM, BAX, BRCA1, CDKN2A, MSH2, NF1, PTEN, RB1, TP53, TP73, TP73L, TSC1, WT1.
Regulation of the Cell Cycle: BRCA2, CDC2, CDC25A, CDK4, E2F1, E2F3, HK2, IGF1R, KRAS, PPM1D, PRKCA, STAT1, TADA3L, TP53BP2.
Other Cell Cycle Genes: BIRC5, CCNH, CCNB2, ESR1, MLH1, PCNA, PRC1.

Cell Growth, Proliferation and Differentiation Genes:
Negative Regulation of Cell Proliferation: BAI1, BCL2, BTG2, CDKN1A, CDKN2A, CHEK1, GML, IFNB1, IL6, MDM2, MDM4, NF1, PCAF, PPM1D, SESN1.
Positive Regulation of Cell Proliferation: IGF1R, IL6.
Cell Proliferation: BRCA1, CDC25A, CDC25C, CDK4, E2F1, MYC, PCNA, PRKCA.
Cell Growth and Differentiation: ESR1, MCL1, MYOD1.
Other Genes Related to Cell Growth, Proliferation, and Differentiation: EGR1, FOXO3A, JUN, KRAS, PTTG1.

DNA Repair Genes: ATM, ATR, BRCA1, BTG2, CCNH, DNMT1, GADD45A, MSH2, PCNA, PTTG1, TP53, XRCC5.