Adams and Victor's Neurology关于帕金森氏病症状论述

A tetrad of hypo- and bradykinesia, resting tremor, postural instability, and rigidity are the core features of Parkinson disease. These are evident as an expressionless face, poverty and slowness of voluntary movement, "resting" tremor, stooped posture, axial instability, rigidity, and festinating gait. Much can still be gained from perusal of the often-cited study by Hoehn and Yahr, published in 1967 before the widespread use of L-dopa. Table 39-3 is reproduced from that paper.南京脑科医院神经内科陶拓宇
帕金森氏病4个核心症状：运动减少和运动缓慢、静止性震颤、姿势不稳和强直。
postural instability：Impairment of balance when standing, walking, or turning.
 Adams and Victor"s Neurology > Chapter 39. Degenerative Diseases of the Nervous System > Diseases Characterized by Abnormalities of Posture and Movement > Parkinson Disease > Clinical Features >

 

 

Table 39-3 Initial Symptoms in Patients with Parkinson Disease
 
 
Tremor 70%
Gait disturbance 11%
Stiffness 10%
Slowness 10%
Muscle aches 8%
Loss of dexterity 7%
Handwriting disturbance 5%
Depression, nervousness, other psychiatric disturbance 4%
Speech disturbance 3%
 

Source: Adapted from Hoehn and Yahr"s study of 183 idiopathic cases, 1967.