代谢综合征的临床诊断标准2009-10-5

                 Criteria for Clinical Diagnosis of the Metabolic Syndrome

Measure 台州市中心医院中西医结合科张茂华	Categorical cut points
Elevated waist circumference	Population- and country-specific definitions
Elevated triglycerides (drug treatment for elevated triglycerides is an alternate indicator)	>150 mg/dL
Reduced HDL cholesterol (drug treatment for reduced HDL cholesterol is an alternate indicator)	<40 mg/dL for males and <50 mg/dL for females
Elevated blood pressure (drug treatment for elevated blood pressure is an alternate indicator)	Systolic >130 mm Hg and/or diastolic >85 mm Hg
Elevated fasting glucose (drug treatment for elevated glucose is an alternate indicator)	>100 mg/dL

October 12, 2009 ? A new joint statement from a number of professional organizations has identified specific criteria for the clinical diagnosis of the metabolic syndrome, tightening up the definition, which previously differed from one organization to the next .

The statement, published online October 5, 2009, in Circulation, includes the participation of the International Diabetes Federation(IDF), the National Heart, Lung, and Blood Institute(NHLBI), the World Heart Federation, the International Atherosclerosis Society, and the American Heart Association(AHA) and is an attempt to eliminate some of the confusion regarding how to identify patients with the syndrome.

The metabolic syndrome has received significant attention because of its role in disease. In general, patients with this syndrome exhibit a proinflammatory state, and, in addition to high serum levels of triglycerides and low levels of high-density lipoprotein cholesterol, they tend to have high levels of apolipoprotein B and elevations in small low-density lipoprotein particles. All of these factors contribute to doubling the risk for incident cardiovascular disease within 5 to 10 years as well as a 5-fold increase in the risk for incident type 2 diabetes.