- Use of non-aspirin NSAIDs during pregnancy may increase the risk of spontaneous abortion
- 作者:邹峻|发布时间:2013-06-21|浏览量:570次
context
nsaidsare one of the commonest classes of drugs taken by pregnant women. data about the risks associated with this remains equivocal. the study by nakhai-pour et al explored whether the use of nsaidsduring pregnancy is associated with increased risk of spontaneous abortion.复旦大学附属华东医院免疫风湿科邹峻
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this study examined data from one province in canada extracted from a provincial database. women who had had a spontaneous abortion (n=4705) were matched with 47 050 controls. the use of nsaidswas measured by whether or not the women filled a prescription for them during their pregnancy. statistical analysis was carried out to explore whether there was any association between the use of non-aspirin nsaidsand the risk of spontaneous abortion.
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the use of nsaidsduring pregnancy appeared to be associated with increased risk of spontaneous abortion among the women included in the study. other findings indicated that spontaneous abortions were more common among (slightly) older women living in an urban received social assistance who had other co-existing healthcare conditions. women who had a spontaneous abortion had had fewer prenatal visits and were taking more prescription medications than women who did not.