?洛酮在?防重型???後?激性??的?效??

Evaluation of Curative Effect of Naloxone on Prevention of Stress Ulcer after Severe Cerebral Damage
作　者	??清(Yin-Qing Zhang);??民(Han-Min Chen);??河(Guo-He Huang);廖?芳(Sheng-Fang Liao);尹家和(Jia-He Yin)
刊　名	?床????
卷期／出版年月	32卷4期(2004/08)
?次	16-17
?料?文	中文
摘要	目的　?察?洛酮?防重型???????激性??的?效。方法　126例重型???患者在常?治?基?上??分?3?：?洛酮?防?44例，?予?洛酮0.3mg•kg^(-1)•d^(-1)，用生理?水100ml持?24b?慢?滴，3d後?至4mg/d；?美拉唑?防?43例?予?美拉唑40mg+生理?水100ml?滴，1次/d；硫糖??防?39例?予硫糖?1.0g，口服，4次/d。2周後停?。?察住院期?各??激性??出血的?生率。?果　?洛酮?防?出血3例，占6.8%；?美拉唑?防?出血4例，占9.3%；硫糖??防?出血15例，占38.5%。?洛酮???美拉唑?比?，差???著意?(P>0.05)。?洛酮??硫糖??比?，差?有?著意?(P<0.05)。??　重型????後早期?防性?用?洛酮能有效?少?激性??出血的?生。 Objective To observe the curative effect of naloxone on the prevention of stress ulcer after severe cerebral damage. Methods 126 cases of severe cerebral damage were at random divided into 3 groups, i. e. naloxone (44), omeprazole (43), and ulcerlmin (39) groups in addition to routine treatment. Results After a period of treatment, here were 3 (6.8%), (9.3%) and 15 (38.5%) cases of ulcerative bleeding in naloxone, omeprazole, and ulcerlmin groups respectively. Clear difference existed between naloxone and ulcerlmin groups (P<0.05), while no difference was found between naloxone and omeprazole groups (P>0.05). Conclusion It is suggested that the incidence of stress ulcer bleeding can be prevented under the condition of administration of naloxone after severe cerebral damage.晋江市中医院脑外科张银清
???	重型????,?洛酮,?激性??;severe cerebral damage,naloxone,stress ulcer
CEPS分?	?科?>???生命科?>??